General description
CD4 is a 55-kD glycoprotein expressed on the surface of T-helper/regulatory T-cells,monocytes, macrophages, and some dendritic cells. The majority of peripheral T-celllymphomas are derived from the T-helper/regulatory cell subset so most matureT-cell neoplasms are CD4+. Anti-CD4 is used to identify normal T-cells and to aid in theidentification of neoplasms of T-cell origin.
Legal Information
Cell Marque is a trademark of Sigma-Aldrich Co. LLC
Linkage
CD4 Positive Control Slides, Product No. 104S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
Other Notes
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Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and ﹤0.1% Sodium Azide
Preparation Note
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Quality
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